ANTIBACTERIAL ACTIVITY OF CYPERUS ROTUNDUS AND MIMOSA PUDICA BASED ON PARAMETERS OF NUMBER OF COLONIES OF TEST BACTERIA AND VALUE OF PHENOL COEFFICIENT

Abstract

Weeds Cyperus rotundus and Mimosa pudica contain various antibacterial compounds that have the potential as antiseptics. The ability of an antiseptic is assessed by testing the coefficient of phenol and its antibacterial power. This study reported the infusion activity of Cyperus rotundus and Mimosa pudica on the number of bacterial colonies of S.epidermidis, S.aureus, E.coli, P.aeruginosa, and S.typhi, as well as the value of the phenol coefficient. This research design only with control group design uses the dilution method. The treatment effect of a single preparation and a combination of 50%, 75%, 100%, and 100% of C.rotundus rhizome infusion and 100% M. pudica leaves showed that the number of test bacteria was significantly different. The smallest number of test bacteria was obtained in the 100% infusion combination treatment. Combination infusion of C.rotundus and M. pudica against S.epidermidis, S.aureus, E.coli, and P.aeruginosa, except for S.typhi produced an effect equivalent to 70% alcohol, and the phenol coefficient value was close to 5% phenol. In conclusion, the combined activity of C.rotundus and M.pudica infusion on the number of tested bacterial colonies and from the value of the phenol coefficient can be developed as an alternative antiseptic.